Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 92 |
Sr. Scientist, Clinical Pharmacology
Cambridge, Massachusetts
The Sr. Scientist in Clinical Pharmacology position will support a rapidly expanding clinical portfolio of promising RNAi therapeutics. The candidate in this position should be well versed in PK and PD with strong ability to critically eval...
4h
| Job Type | Full Time |
Associate Director, Case Management Vendor Oversight
Cambridge, Massachusetts
Overview The Associate Director, Case Management Vendor Oversight (CMVO), Global Safety Operations is responsible for implementing processes and procedures to support the oversight of ICSR processing activities as well as maintaining regula...
4h
| Job Type | Full Time |
Regional Business Director - TTR (MA, RI, NH, ME)
Cambridge, Massachusetts
Overview We are looking for an experienced Regional Business Director (RBDs to support the promotion of AMVUTTRA (vutrisiran). The U.S. Food and Drug Administration (FDA) recently approved the supplemental New Drug Application (sNDA) for AM...
1d
| Job Type | Full Time |
Senior Scientist, Statistical Genetics
Cambridge, Massachusetts
Overview The Alnylam Human Genetics (AHG) team is looking for a passionate and driven scientist to apply human genetics to drug discovery and development. The successful candidate will perform comprehensive analyses of human genetic data to...
1d
| Job Type | Full Time |
Manager, Clinical Risk and Analytics
Cambridge, Massachusetts
Overview The Manager, Clinical Risk & Analytics (CR&A) reports into the CR&A function and is responsible for cross-functional risk management and central monitoring activities for their assigned clinical trials in accordance with ICH GCP E6...
2d
| Job Type | Full Time |
Director, Global Customer Engagement Platforms
Cambridge, Massachusetts
Overview: The Director,GlobalCustomer Engagement Platforms leads business product ownership for Alnylam's CRM and CDP ecosystems, ensuring they enable compliant, data-driven customer engagement across the U.S., with a clear eye toward scala...
2d
| Job Type | Full Time |
Director, Global Content Enablement Platforms
Cambridge, Massachusetts
Overview: The Director,GlobalContent Enablement Platformsis responsible forbusiness ownership of Alnylam's web content platforms and for defining the standards, governance, and operatingmodelthat enable compliant, scalable digital publishin...
2d
| Job Type | Full Time |
Director, Global Omnichannel Operations
Cambridge, Massachusetts
Overview: The Director, Global Omnichannel Operations is responsible for establishing and leading Alnylam's omnichannel operating discipline, the playbooks, workflows, quality controls, and ways of working that make campaign execution predi...
2d
| Job Type | Full Time |
Business Account Executive, TTR - San Antonio, TX
Cambridge, Massachusetts
Overview We are looking for experienced Business Account Executives (BAEs) with specialty sales experience to promote AMVUTTRA. hATTR patients often spend years undiagnosed and misdiagnosed. This is an amazing opportunity to educate and enh...
2d
| Job Type | Full Time |
Cambridge, Massachusetts
CTMS Administrator Overview The CTMS Administrator is responsible for performing the day-to-day operations and support of the Alnylam Clinical Trial Management System (CTMS) for the execution of clinical trials across the development portfo...
2d
| Job Type | Full Time |