Research Senior Technician

Join the Dynamic Team at the Thoracic Oncology Research Collaborative Hub (TORCH) led by Dr. Carbone

Position Overview: TORCH is looking to fill the position of Research Technician 3 in the laboratory of Dr. Carbone. As the director of the James Thoracic Center, Dr. Carbone has a research lab and mentors multiple PIs. He also participates in many collaborative research and clinical projects. Together we make up the Thoracic Oncology Research Collaborative Hub (TORCH). Our group focuses on lung cancer research and translational therapeutics, including immunotherapies.

This position will provide support to senior lab members that support the Carbone lab specifically, and TORCH more broadly. As a result, this individual can be assigned to multiple projects as needed. As we are ever-growing collaborative group, there is also a need for the individual to support lab organization.

Opportunities for Employees: We are committed to supporting employees in discovering their passions and advancing their educational and career goals. Depending on time and interest, students are encouraged to pursue their own projects and apply for grants (if applicable).

Motivated Individuals: We seek driven individuals who thrive in a team setting and who are passionate about supporting our mission to understand lung cancer mechanisms and develop innovative treatments.

Our Mission: Our mission is simple yet profound: end cancer. We aim to improve and extend the quality of life for lung cancer patients worldwide.

Training provided:

• Hands-On Training:
  • As a new employee in TORCH, you will receive hands-on training in essential molecular biology techniques such as RNA/DNA/Protein extraction, Western Blotting, PCR genotyping, bacterial cloning, cell culture, and mouse work, depending on the needs of the project(s) assigned.
  • Once you have received the standard training we will support and provide trainings required for specific projects to which you are assigned.
• Compliance and regulatory trainings:
  • There are regulatory and compliance-based trainings that differ depending on work being done. These trainings are required before any work may begin.
    • These can be either computer-based (CBLs) or in-person trainings.

Requirements:

• The wet lab setting incorporates both basic biological and translational techniques.
  • Performing and assisting with a variety of molecular biology techniques, including protein/DNA/RNA isolations, Western blots, PCR techniques, bacterial cloning etc.
  • Preparing samples for flow cytometry and cell sorting, including spectral flow cytometry
  • Performing a large variety of cell culture techniques, including primary cell culture, generating new cell lines, and processing tissue (human and murine) into single cell suspensions
  • Monitoring animal health
  • Performing a variety of procedures on mice, including injections, bleeding, oral gavage, weighing, handling, ear tagging, ear punching, euthanasia, etc.
  • Processing a variety of mouse tissues and blood samples for downstream analysis
  • Processing human blood samples and isolating human immune cell subtypes.
• Documentation:
  • Records, consolidates, and assists with analysis of research results.
  • Assists in evaluating validity of data obtained from experimental procedures by performing data analysis and other statistical techniques on sample data.
  • Summarizes data for inclusion in grant proposals and manuscripts, assisting with writing and figure generation for manuscripts at the direction of the supervisor.
  • Prepares research progress reports; assists senior lab members and principal investigator(s) with the preparation of publications, manuscripts, articles, posters, and abstracts.
  • May need to independently review relevant scientific literature to ensure protocols are up to date and to troubleshoot procedures.
• Lab Maintenance:
  • Take part in maintaining the laboratory through identified laboratory procedures and practices.
  • Sets up and operates laboratory equipment as well as routine cleaning and maintenance.
  • Participate in lab meetings and journal clubs.
  • Assists with training of junior research staff, and undergraduate and graduate students in research methods and equipment operation.
  • Monitors general supply inventories and initiates procurement requests as needed.
  • Assists Lab Supervisor with organization of the lab; creating and maintaining electronic inventories of reagents (i.e. antibodies, enzymes, etc.), equipment information, and other tasks as determined.

Minimum Required Qualifications - Education and Experience:

• Bachelors degree in a biological, health or other related science field or equivalent experience required. Requires successful completion of a background check; qualified candidates may be asked to complete a pre-employment physical including a drug screen.
• Ability to work well within a team environment.

Desired Experience (Preferred but not Required):

• Self-motivated, and good time management skills
• Strong organizational skills
• Proficiency with Microsoft Office 365 (excel, word etc.)
• Previous experience in research or a lab environment is preferred but not required.

Commitment and Teamwork:

• Support experiments, collaborate with fellow students and lab staff, report results, and prepare presentations.
• A strong willingness to work in a team environment is essential.

Timeline: We are replacing a great individual (to graduate school, yay!) and would like the new hire to train with them. If interested apply sooner rather than later.

Final Note: We strive to end cancer while enhancing and extending the lives of lung cancer patients through cutting-edge research and compassionate collaboration.

Additional Job Description

The Ohio State University is a dynamic community of diverse resources, where opportunity thrives and where individuals transform themselves and the world. The Ohio State University is one of the nations largest and most comprehensive public universities and a top employer in Ohio.

As one of only 54 designated comprehensive cancer centers in the nation, The Ohio State University Comprehensive Cancer Center Arthur G. James Cancer Hospital and Richard J. Solove Research Institute is dedicated to the creation of knowledge in laboratory, clinical and population-based cancer research. We apply those discoveries to develop more effective approaches to cancer prevention, diagnosis, and therapies providing tomorrows standard of care today. A Cancer-Free World Begins Here.

The OSUCCC James is the only cancer program in the United States that features a National Cancer Institute (NCI)-designated comprehensive cancer center aligned with a nationally ranked academic medical center and a freestanding cancer hospital on the campus of one of the nations largest public universities. is the only cancer program in the United States that features a National Cancer Institute (NCI)-designated comprehensive cancer center aligned with a nationally ranked academic medical center and a freestanding cancer hospital on the campus of one of the nations largest public universities.