New 
Research Associate 2 in vivo musculoskeletal research
 BioMarin Pharmaceutical Inc. | |
life insurance, paid time off
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 United States, California, Petaluma | |
 Apr 15, 2025 | |
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Who We Are We are seeking a motivated Research Associate 2 with extensive in vivo experience to join the MSK in vivo team to design and execute key studies to transform the lives of people with rare musculoskeletal diseases.
The primary role of the Research Associate 2 will the execution of in vivo studies as part of the musculoskeletal in vivo team. They will work collaboratively across the Research in vivo group in the Musculoskeletal group as well as other in vivo therapeutic areas as needed to execute project strategies for in vivo testing of novel therapeutics.
The successful candidate will have a strong background in in vivo techniques and demonstrated experience in the use of animal model systems in research. Experience with rodent in vivo models of disease and a collaborative mindset is critical. Experience with muscular or skeletal biology and disease is desirable. While some industry experience is a plus, it is not required.
The successful candidate will contribute in vivo model evaluation and support to project teams that support the project goals. Including hands on in vivo study performance as well as application of in vivo methods and techniques. Strong written communication skills are critical for writing IACUC protocols, communicating scientific results, monitoring in vivo studies and tissue collection, and sample management. The successful candidate must have extensive experience with multiple methods of dosing techniques (IM, IP, IV, SC, PO), Necropsy, tissue collection and preferred experience with other in vivo analytic techniques including plethysmography, gait analysis, Biomechanical evaluation of bone, Histology, Computerized Tomography, Multiphoton microscopy and IVIS imaging.
The ideal candidate will have a bachelor's or equivalent scientific degree in Biology or related science. The ideal candidate will have hands-on experience with dosing and data collection in animal models of disease, a proven track record of high-quality science, proficiency with in vivo methods such as administration of test articles, perfusion and tissue collection, blood collection, with rodent surgical experience preferred. Candidate level at hire will depend on education and experience.
Responsibilities:
Support Research Program
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Conduct in vivo dosing support and execution of studies including IV, IM, SC, IP, and PO dosing for research on genetic muscle and skeletal diseases
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Contribute to novel therapeutic programs based on innovative, ground-breaking discoveries that could lead to new, high-impact opportunities for patients
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Participate and collaborate in writing, review and contribution to study synopses, protocols, study reports and regulatory documents
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Collaborate with various BioMarin functions, to collaboratively ensure appropriate/timely progression of projects
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Excellent written and verbal communication
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Ability to build/foster productive cross-functional collaborations both within and external to BioMarin
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Execute hands-on responsibilities including but not limited to animal handling and restraint (rodents), administration via various routes of administration, including intravenous (tail-vein), in-life animal health monitoring and measurements, clinical observations, sample collection and processing, and accurate data collection. In addition, providing daily care and monitoring of mice or rats, including health checks and documentation, will also be required.
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Follow all institutional, local, and federal regulations regarding animal care and use. Adhere to safety protocols and maintain a clean and organized work environment. Maintain detailed and accurate records of all procedures and animal health status including adverse study events. Meticulous electronic lab notebook documentation.
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Communicate experimental plans and results to the project team. Support product development and regulatory filings for pivotal clinical studies.
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Follow instructions and work independently to effectively manage time and prioritize tasks to ensure all
assignments are completed on or before deadlines.
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Share your knowledge and understanding with other team members
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Document experimental methods and outcomes using Electronic Lab Notebooks and generation/maintenance of technical procedure documents and SOPs.
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Willingness to work on site full time including off hours and weekends based on study needs.
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Other duties as assigned
General requirements for the position:
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Strong analytical, problem-solving, and decision-making skills
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Strong understanding of genetically engineered models, breeding of rodents
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Excellent oral and written communication skills
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Passion for contributing your scientific skills to develop therapies for patients in need
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Must be able to utilize computer databases for data analysis, data entry, and point of care observations
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Must be able to work under time constraints with minimal direction of day-to-day responsibilities, including collaboratively working with multidisciplinary teams
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Must be able to work with external regulatory agencies and accreditation groups
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Some "off-core business hours" work required
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Complete all company training requirements
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Perform all work per designated safety standards and comply with Personal Protective Equipment requirements and occupational health to perform work tasks
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This position is an on-site critical required position
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Other duties as assigned
Education and Experience Requirements:
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Bachelor's degree in a related subject area or equivalent amount of previous related experience in in vivo study execution
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Extensive hands-on experience with rodent in vivo work with preference in the musculoskeletal field
This position is full-time on-site and based in Petaluma, CA with occasional work on site in San Rafael, CA
Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned.
The salary range for this position is: $77,600 to $116,400. BioMarin considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans.
Equal Opportunity Employer/Veterans/Disabled An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. For additional benefits information, visit: https://careers.biomarin.com/benefits.
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