Assistant Research Professor

Job Summary:

This position entails intensive research into how chromosome entanglements, persisting from prior replication difficulties, are dealt with in mitosis. This research involves molecular genetic manipulation of fission yeast as well as mammalian cells, structural analysis of DNA molecules purified from cells, extensive quantitative microscopy and cell culture.

Key Responsibilities:

• 30% of time: Contribute to conceptual and experimental design for project, solve experimental problems, plan each approach from start to finish. Analyze and interpret data, in consultation with PI. Learn, understand and contribute to all other colleagues' projects in the lab. Read relevant literature. Participate actively in lab and departmental meetings. Present research and learn about others' research in seminars and posters at national and international conferences. Plan, prepare and revise manuscripts in consultation with PI. Plan, prepare and revise grant proposals in consultation with PI.
• 70% of time: Fission yeast strain construction and husbandry; mammalian cell culture. Genetic manipulation of both yeast and mammalian cells; cell synchronization. Molecular analysis of DNA arrangement and structure including pulsed field gel electrophoresis, southern blots, purification of entangled DNA from mitotic cells, analysis by electron microscopy and enzyme sensitivity. Phosphoproteomic screen implementation and analysis including bioinformatics; synthetic genetic array screen implementation and analysis. Extensive microscopy of fission yeast and mammalian cells, both live and fixed, structured illumination microscopy, quantitative image analysis.

Work Location:

Onsite - this role is expected to work onsite and is located in Aurora, CO

Why Join Us:

The Department of Biochemistry and Molecular Genetics has 4 missions:

• Research: to investigate important questions regarding basic biological mechanisms and how they relate to health and disease, and translate the answers into practical applications when possible.
• Training: to prepare students and postdoctoral fellows for productive careers in academia and
• industry.
• Teaching: to transmit an understanding of the principles of biochemistry and molecular genetics to future physicians (medical students) and scientists (medical and graduate students).
• Service: to provide expertise and resources to our colleagues at the University of Colorado, and to communicate our knowledge of and excitement for science to the broader community.

The Department strives to provide a collegial, interactive and supportive environment and infrastructure to enable us to achieve those goals.

Why work for the University?

We have AMAZING benefits and offer exceptional amounts of holiday, vacation and sick leave! The University of Colorado offers an excellent benefits package including:

• Medical: Multiple plan options
• Dental: Multiple plan options
• Additional Insurance: Disability, Life, Vision
• Retirement 401(a) Plan: Employer contributes 10% of your gross pay
• Paid Time Off: Accruals over the year
• Vacation Days: 22/year (maximum accrual 352 hours)
• Sick Days: 15/year (unlimited maximum accrual)
• Holiday Days: 10/year
• Tuition Benefit: Employees have access to this benefit on all CU campuses
• ECO Pass: Reduced rate RTD Bus and light rail service

There are many additional perks & programs with the CU Advantage.

Equal Opportunity Statement:

The University of Colorado (CU) is an Equal Opportunity Employer and complies with all applicable federal, state, and local laws governing non-discrimination in employment. We are committed to creating a workplace where all individuals are treated with respect and dignity, and we encourage individuals from all backgrounds to apply.

Qualifications:

Minimum Qualifications:

Applicants must meet minimum qualifications at the time of hire.

• Ph.D. in molecular or cell biology, genetics or a related field. At least 5 years experience and deep understanding of chromosome biology and yeast genetics.

Preferred Qualifications:

• Expertise in protein purification and analysis of posttranslational modifications. Expertise in genomewide screening approaches and bioinformatic analysis. Demonstration of experimental rigor and innovativeness. Excellent communication skills.

How to Apply:

For full consideration, please submit the following document(s):

1. A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position

2. Curriculum vitae / Resume

3. Five professional references including name, address, phone number (mobile number if appropriate), and email address

Applications are accepted electronically ONLY at www.cu.edu/cu-careers.

Questions should be directed to: Shelly Fortner, Shelly.Fortner@cuanschutz.edu

Screening of Applications Begins:

Immediately and continues until April 16, 2025.

Anticipated Pay Range:

The starting salary range (or hiring range) for this position has been established as HIRING RANGE:

$100,000

The above salary range (or hiring range) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting. This position is not eligible for overtime compensation unless it is non-exempt.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.

Total Compensation Calculator: http://www.cu.edu/node/153125

ADA Statement:

The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.adacoordinator@ucdenver.edu.

Background Check Statement:

The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.

Vaccination Statement:

CU Anschutz strongly encourages vaccination against the COVID-19 virus and other vaccine preventable diseases. If you work, visit, or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz, you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work, visit, or volunteer, respectively. In addition, if you work in certain research areas or perform certain safety sensitive job duties, you must enroll in the occupational health medical surveillance program.