New

Research & Design Engineer

Massachusetts General Hospital
United States, Massachusetts, Newton
2014 Washington Street (Show on map)
Jan 10, 2025
GENERAL SUMMARY/OVERVIEW STATEMENT: The Charles P. Lin Lab is a leading biomedical optics group at the MGH Wellman Center for Photomedicine, focused on the development of advanced optical techniques (confocal and multiphoton microscopy, in vivo flow cytometry, scanning laser ophthalmoscopy, etc.) for studying the production of blood cells in the bone marrow (the hematopoietic system). Once formed, the blood cells are released into the circulation to deliver oxygen (red blood cells) and carry out immune functions (white blood cells) throughout the body. A new translational effort aims to image the movement of white blood cells in blood vessels, providing a new way of assessing inflammation in human patients noninvasively. To accelerate this project, the Software Engineer will develop an automated machine learning and image processing pipeline for detecting and tracking white blood cells from image data. This project aims to address major diagnostic limitations in low-resource settings. As part of our team, you will work with a multidisciplinary group of experts in optics, engineers, biologists, and physicians. PRINCIPAL DUTIES AND RESPONSIBILITIES: Design and develop mechanical systems, components, and assemblies using CAD software (e.g., SolidWorks). Use 3D printers (e.g., Formlabs) to print the mechanical parts, inspect them, and make necessary improvements. Integrate various optics and electronics into the 3D-printed mechanical components. Help to characterize the developed microscopes by measuring the magnification, field of view, and optical resolution. Develop basic electronic circuits to control LEDs, actuators, motorized stages, and electrically tunable lenses. Troubleshoot and resolve technical issues during the prototyping phase. Document processes, methodologies, and findings, ensuring reproducibility of results. Work with cross-functional professionals (postdocs, engineers, research assistants). EDUCATION: BS in biomedical engineering or related fields (mechanical engineering, electrical engineering, physics, etc.) Master's or Ph.D. preferred EXPERIENCE: 3 years' experience working with basic electronic components (LEDs, electric circuits, Arduino, etc.) Excellent problem-solving and analytical skills. Strong communication and teamwork abilities. Preferred: Experience using Zemax Optical studio software. Experience in designing PCBs. Experience with soldering electrical components. Experience with the assembling of compact imaging systems. Basic knowledge of optics and the development of imaging system prototypes is preferred but not necessary. SKILLS/ ABILITIES/ COMPETENCIES REQUIRED: Some understanding of human biology. Able to develop tools that are applicable, robust and meet short- and long-term needs to support assigned projects. Able to perform and incorporate quality work within technical specifications. Can work with attention to detail, following protocols and timelines. Able to self-manage to ensure own learning, productivity and development. Able to identify and refer matters of question and concern. Good communication skills and a collaborative mindset. Ability to effectively document work-related information including processes and outcomes. WORKING CONDITIONS: Normal office conditions with extended periods of time in computer work and keyboarding as well as sitting. Work location is within a research setting on the hospital campus. Hours may be needed outside of standard workweek. Additional_Job_Description The General Hospital Corporation is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.