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Technical Research Assistant I

Brigham and Women's Hospital
United States, Massachusetts, Boston
20 Shattuck Street (Show on map)
Jan 07, 2025
The research assistant has a key role in identifying therapeutic strategies in pediatric and adult cancers. Previous studies by the lab have led to the identification of new therapeutic mechanisms and therapeutic strategies for cancer. The research assistant will juxtapose genomic, protein (immunoblotting), and drug-response studies to identify drugs that target essential biologic features in several related types of cancer. The research assistant will also help develop novel, high-throughput, techniques that allow potential cancer drugs to be evaluated far more efficiently than has been previously possible. Ideally, the research assistant will look forward to preparing manuscripts for publication in high-impact science and medicine journals, so strong writing ability is a plus. Perfect opportunity for someone planning to attend medical or graduate school in 2-3 years!
This laboratory is primarily interested in the biology and therapeutics of cancer.

Principal Duties and Responsibilities:

1. Contributes to genomic and proteomic screens to identify novel therapeutic targets in human cancer. Performs tumor cell cultures and evaluates effects of treating tumor cultures with novel therapies. Carries out standard methods of molecular biology, including: genomic (DNA, RNA) analyses by high-throughput sequencing, protein analyses by immunoblotting, and drug response assays.

2. Records data, summarizes and analyzes results using basic statistics.

3. Reports on progress of work at weekly laboratory seminars.

4. Assists in preparing laboratory reagents and chemicals.

5. Functions as a key team member in preparing high-impact publications.

6. Helps train new research assistants and postdoctoral fellows in standard methods of molecular biology.

7. Maintains established departmental policies, procedures and objectives, including the areas of quality assurance, safety, environmental affairs and infection control.

Education

Bachelor of Science or Bachelor of Arts degree in a biological/physical science required.

Experience

Some laboratory experience desired. Undergraduate coursework or projects will also be considered as appropriate experience and may be credited upon hire if project(s) used methods relevant to our lab research.

Knowledge, Skills and Abilities

Ability to carry out procedures in a coordinated multi-step manner with appropriate consultation.

Ability to methodically record data and to analyze data using basic statistics.

Ability to contribute to manuscript drafts.

Ability to prioritize work.

Physical Requirements

  • Standing Frequently (34-66%)
  • Walking Frequently (34-66%)
  • Sitting Occasionally (3-33%)
  • Lifting Frequently (34-66%) 35lbs+ (w/assisted device)
  • Carrying Frequently (34-66%) 20lbs - 35lbs
  • Pushing Occasionally (3-33%)
  • Pulling Occasionally (3-33%)
  • Climbing Rarely (Less than 2%)
  • Balancing Frequently (34-66%)
  • Stooping Occasionally (3-33%)
  • Kneeling Occasionally (3-33%)
  • Crouching Occasionally (3-33%)
  • Crawling Rarely (Less than 2%)
  • Reaching Frequently (34-66%)
  • Gross Manipulation (Handling) Frequently (34-66%)
  • Fine Manipulation (Fingering) Frequently (34-66%)
  • Feeling Constantly (67-100%)
  • Foot Use Rarely (Less than 2%)
  • Vision - Far Constantly (67-100%)
  • Vision - Near Constantly (67-100%)
  • Talking Constantly (67-100%)
  • Hearing Constantly (67-100%)


The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.
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